The American Psychiatric Association Publishing Textbook of Mood Disorders

This new edition of The American Psychiatric Association Publishing Textbook of
Mood Disorders is a systematic and painstaking reconceptualization of its
predecessor. Under new editorial direction and with a revised roster of expert
contributors, the second edition is an utterly current, clinically competent,
and comprehensive text that will become an instant classic. The book is
structured for learning and easy reference, moving deftly from symptomatology
and epidemiology to pathogenesis and on to somatic interventions,
cognitive-behavioral interventions, and psychotherapy. The latest science on
genetics and epigenetics, brain imaging, and neurobiology are also examined in
depth. Critically important to the clinician is the section on management of
mood disorders, which provides treatment guidelines for major depressive
disorder and bipolar disorder, as well as information on understanding, and
preventing, suicide in children, adolescents, and adults. Finally, perspectives
are offered on depression among women, children, and geriatric patients, as well
as on depression across cultures. Practicing psychiatrists, residents, and
students alike will benefit from the book's inclusive coverage.

Topics new
to this edition include the following: Treatment-resistant depression-its
definition and approaches to its treatment-is addressed in a dedicated chapter
that covers diagnostic accuracy, pseudoresistance, comorbidity, pharmacological
management, adjunctive strategies, psychotherapy, neuromodulation, and novel and
experimental therapies. Investigational agents, most notably ketamine and its
relatives, constitute an exciting frontier in the treatment of mood disorders,
and the clinical application, routes of delivery, dosing, risks, and clinical
trials are explored in a dedicated chapter that is both rigorous and thorough.
There is compelling evidence that childhood maltreatment (defined as exposure to
emotional, physical, and sexual abuse and neglect before the age of 18 years) is
a prominent risk factor for the development of mood disorders as well as for a
pernicious course and poor treatment response in mood disorders. These findings,
as well as the underlying neurobiological and environmental interactions that
may contribute to the development of mood disorders, are examined thoroughly and
thoughtfully. As our understanding of immune function in mood disorders has
grown, psychoneuroimmunology has emerged as a focus of study likely to make
major contributions to clinical practice in the coming decades. The book updates
readers on this promising area of research.

Over the last decade,
depression has emerged as the leading cause of disability worldwide, with
significant attendant morbidity and mortality. The American Psychiatric
Association Publishing Textbook of Mood Disorders equips clinicians and trainees
with the knowledge they need to alleviate suffering in their patients with mood
disorders.