The American Psychiatric Association Practice Guideline for the Prevention and Treatment of Delirium

Prevalence rates of delirium range widely depending on patient population and
treatment setting. Information on rates of delirium in community settings is
limited, but in emergency and hospital settings, one-quarter or more of the
patients will experience delirium. Rates can be even higher in older
individuals, critical care patients, and patients who have had major orthopedic
or cardiovascular surgeries.

Prevention, early detection, and optimal
treatment are critical because delirium is often unrecognized and is associated
with increased morbidity and mortality. For example, postsurgical delirium has
been reported to have a 30-day mortality rate of up to 10%, versus 1% in
postsurgical patients without delirium. Additionally, delirium exacts a
significant economic toll on individuals, their families, and society because of
longer hospital stays, ICU admissions, rehospitalizations, and lost wages. In
the United States, direct health care costs of hospitalized older adults with
delirium are significantly higher than hospitalized patients without delirium,
even after adjusting for demographic and clinical factors.

The American
Psychiatric Association Practice Guideline for the Prevention and Treatment of
Delirium reviews current evidence-based nonpharmacological and pharmacological
interventions to prevent or treat delirium in adults. In addition, it includes
statements related to assessment and treatment planning, which are an integral
part of patient-centered care. The guideline describes approaches to
implementing recommendations and suggestions in clinical practice. By providing
up-to-date knowledge, the guideline aims to help clinicians feel more confident
in preventing, recognizing, and treating delirium, thereby improving the care
and well-being of their patients.Evidence tables, literature search results,
clinical questions, and more for this guideline can be found in the online
appendixes.