Aptasensors for Point-of-Care Diagnostics of Cancer: From Lab to Clinics

The aptasensor-based point-of-care testing devices offer high sensitivity and specificity They are cost-effective, provide rapid detection, and are stable in an adverse environment making them suitable tools for on-site detection of cancer biomarkers in medical and clinical settings.The present book emphasizes the target-specific design, functionalization, and synthesis of aptamers for the fabrication of aptamer-based biosensors which can be employed for cancer biomarkers detection. This book will provide the reader with a timely update on the recent advances in aptamers-based point-of-care biosensors for cancer diagnostics.It will also demonstrate the advantages of aptamers such as low cost, ease of design, synthesis, and modification, hence can be employed as a good alternative to antibody-based biosensors. It will also shed light on nanostructured materials and their significance for the construction of point-of-care aptasensors. Furthermore, it will describe in detail the integration of a point-of-care aptasensors-based sensing platform integrated with a wireless platform (internet-of-medical things) for intelligent disease management.Key Features: Highlights strategies for the synthesis of aptamers along with the design and fabrication of aptasensor-based point-of-care devices for early detection of cancer biomarkers and how these sensors can revolutionize the field of disease diagnostics. Details the technology of aptasensor-based point-of-care devices for disease diagnosis, with a specific focus on cancer diagnostic applications. Includes detailed information on the integration of aptasensor-based point-of-care technologies on the wireless platform internet-of-medical things for smart and intelligent disease management. *Authors of the chapters of this book are well-known researchers in the field of cancer diagnostics and have incorporated specific case studies within their respective chapters.